I played around with Topaz denoise, and I must say that I am pretty impressed! Normally, the differences between all denoise softwares are pretty marginal (and I tested lots of them!), but Topaz works drastically differently!
At first, I was like "C'mon! This piece of sh** isn't even doing a profile before denoising!"...and i must say that if you play with the sliders, the results are nothing short of amazing!
However, I will continue to use Neat Image for most of my pics, simply because Topaz is SOOOOO SLLOOOOOOOOWWWW! That is a shame!
Well, anyway, thank you for the tip